Down syndrome, often known as Down’s syndrome mainly around the Uk or trisomy 21, is really a chromosomal illness which occurs due with the presence of all or an additional component of chromosome 21. The syndrome is named just after the British doctor John Langdon Down who initial gave the outline of the condition in 1866. The clinical information of the illness got during the nineteenth century by Jean Etienne Dominique Esquirol in 1838 and Edouard Senguin 1844. Dr. Jerome Lejeune in 1959 recognized that Down syndrome crops up owing to trisomy of chromosome 21. The identification of this syndrome on the fetus are generally finished by chorionic villus sampling or amniocentesis in pregnancy or soon after the beginning within the baby. The effects and extent from the added duplicate of chromosome 21 fluctuate among individuals and may depend upon the genetic history and pure probability.
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